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RGUHS Nat. J. Pub. Heal. Sci Vol: 14  Issue: 2 eISSN:  pISSN

Original Article

A Study on clinical profile of meconium aspiration syndrome in relation to gestational age and birth weight and their immediate outcome

Grishma Hirani*, Rupinder Kaur*, Basanthkumar GR**, Guruprasad G**, Gayathri H.Aradhya*** 

*Resident, **Professor, ***Associate Professor, Gayathri H.Aradhya, Department of Paediatrics, JJM Medical College, Davangere, Karnataka

 

Corresponding author:

Dr. Grishma Hirani Resident Department of Pediatrics JJM Medical College Davanagere, Karnataka Email : grishmahirani@gmail.com 

Year: 2015, Volume: 5, Issue: 3, Page no. 60-65,
Views: 817, Downloads: 50
Licensing Information:
CC BY NC 4.0 ICON
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0.
Abstract

Introduction: Meconium stained amniotic fluid (MSAF) varies between 5 to 25% while Meconium aspiration syndrome (MAS) occurs in 2 approximately 5% of infants born through MSAF. Even with advanced care, mortality rate from MAS remains high at 3-5 % . MAS occurs from 3,4 mild to severe form. Incidence rate of MAS varies widely in different institutes.

Objectives: To review the clinical profile of MAS in neonates in relation to birth weight and gestational age and their immediate outcome. Methods:This study was done in cases admitted to NICU with MAS. The babies who were born with meconium stained liquor were admitted to NICU and diagnosis of MAS was made depending upon the clinical criteria and were observed for immediate outcome.

Results: During this study period, out of 3294 deliveries, 332 (10.07%) babies had meconium stained liquor and 29 (0.88%) babies developed MAS. Total 9 (31.03%) cases required ventilatory support, with mortality of 8 (27.58%)

Conclusion: Increased incidence of MAS was associated with increase in gestational age, birth weight >2.5 kgs and caesarean deliveries. MAS carries high morbidity and mortality rate. Hence proper diagnosis and timely intervention should be done to reduce this.

<p><strong>Introduction:</strong> Meconium stained amniotic fluid (MSAF) varies between 5 to 25% while Meconium aspiration syndrome (MAS) occurs in 2 approximately 5% of infants born through MSAF. Even with advanced care, mortality rate from MAS remains high at 3-5 % . MAS occurs from 3,4 mild to severe form. Incidence rate of MAS varies widely in different institutes.</p> <p><strong>Objectives: </strong>To review the clinical profile of MAS in neonates in relation to birth weight and gestational age and their immediate outcome. Methods:This study was done in cases admitted to NICU with MAS. The babies who were born with meconium stained liquor were admitted to NICU and diagnosis of MAS was made depending upon the clinical criteria and were observed for immediate outcome.</p> <p><strong>Results: </strong>During this study period, out of 3294 deliveries, 332 (10.07%) babies had meconium stained liquor and 29 (0.88%) babies developed MAS. Total 9 (31.03%) cases required ventilatory support, with mortality of 8 (27.58%)</p> <p><strong>Conclusion: </strong>Increased incidence of MAS was associated with increase in gestational age, birth weight &gt;2.5 kgs and caesarean deliveries. MAS carries high morbidity and mortality rate. Hence proper diagnosis and timely intervention should be done to reduce this.</p>
Keywords
Acute respiratory failure ,meconium aspiration syndrom, neonate.
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