Article

JOURNAL MENU
Cover
Journal Cover Page

RGUHS Nat. J. Pub. Heal. Sci Vol: 14  Issue: 2 eISSN:  pISSN

Original Article

Neonatal septicemia and antibiogram: Paediatrician's Challenge

V. L. Jayasimha1*, ,K.G Raghukumar2, Vinod Kumar C.S3, Satish S Patil4, K.G. Basavarajappa5

1Professor,2,3,4Associate Professor, 5Professor and Head Department of Microbiology, S.S. Institute of Medical Sciences & Research Centre, Davangere

Received Date: 2016-12-12,
Accepted Date: 2017-01-10,
Published Date: 2017-01-31
Year: 2017, Volume: 7, Issue: 1, Page no. 12-15, DOI: 10.26463/rjms.7_1_6
Views: 626, Downloads: 3
Licensing Information:
CC BY NC 4.0 ICON
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0.
Abstract

Neonatal sepsis is a worldwide problem with the prevalence at 1 to10 per 1000 live births and one of the indicator for measuring the health status of a Nation. According to WHO there are about 5 million neonatal death per year with 98% occurring in developing countries. Antimicrobial resistance is a growing threat worldwide. The present study aimed to know the various bacteria causing neonatal septicemia and their antibiogram. Ours was a Prospective study done over a period of 2 years. Blood samples for culture were collected aseptically before starting antibiotic therapy and subcultures were performed. The isolates were identified by standard biochemical tests and antibiogram of the isolates were studied. Out of 360 cases 160 were bacteriologically positive, Klebsiella was the most common organism isolated (21%), followed by Staphylococcus aureus (20%) Acinetobacter (15%), Pseudomonas (13%).Maximum sensitivity was seen with Linezolid, Erythromycin for Gram positive organisms and Gram negative organisms were sensitive to Piperacillin/ Tazobactum, Imipenem, Levofloxacin, and Meropenem. Findings of our study will enhance the knowledge of likely causative organism causing neonatal septicemia for the clinicians which can in turn help in instituting prompt and appropriate therapy which in turn reduce morbidity and mortality.

<p>Neonatal sepsis is a worldwide problem with the prevalence at 1 to10 per 1000 live births and one of the indicator for measuring the health status of a Nation. According to WHO there are about 5 million neonatal death per year with 98% occurring in developing countries. Antimicrobial resistance is a growing threat worldwide. The present study aimed to know the various bacteria causing neonatal septicemia and their antibiogram. Ours was a Prospective study done over a period of 2 years. Blood samples for culture were collected aseptically before starting antibiotic therapy and subcultures were performed. The isolates were identified by standard biochemical tests and antibiogram of the isolates were studied. Out of 360 cases 160 were bacteriologically positive, Klebsiella was the most common organism isolated (21%), followed by Staphylococcus aureus (20%) Acinetobacter (15%), Pseudomonas (13%).Maximum sensitivity was seen with Linezolid, Erythromycin for Gram positive organisms and Gram negative organisms were sensitive to Piperacillin/ Tazobactum, Imipenem, Levofloxacin, and Meropenem. Findings of our study will enhance the knowledge of likely causative organism causing neonatal septicemia for the clinicians which can in turn help in instituting prompt and appropriate therapy which in turn reduce morbidity and mortality.</p>
Keywords
antibiogram, neonatal septicemia
Downloads
  • 1
    FullTextPDF
Article

None

Supporting File
No Pictures
References

None

We use and utilize cookies and other similar technologies necessary to understand, optimize, and improve visitor's experience in our site. By continuing to use our site you agree to our Cookies, Privacy and Terms of Use Policies.