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RGUHS Nat. J. Pub. Heal. Sci Vol: 14  Issue: 2 eISSN:  pISSN

Case Report

A Rare case report of Isolated thoracic Extra-Duralprimary NonHodgkin's Lymphoma (T-cell rich B cell lymphoma)-TRBCL variant

Varadaraju DN, Satish Babu HV, Sastri S, Ananth G, Santosh KV, Patil SR

Address for correspondence:

Dr. D N Varadaraju, Department of Neurosurgery, Vydehi Institute of Medical Sciences and Research Center, #82, EPIPArea, Whitefield, Bengaluru 560066 varada_82@yahoo.co.in

Department of Neuro-Surgery, and Pathology, Vydehi Institute of Medical Sciences and Research Center, Bengaluru

Year: 2014, Volume: 4, Issue: 1, Page no. 38-40,
Views: 621, Downloads: 4
Licensing Information:
CC BY NC 4.0 ICON
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0.
Abstract

Non-Hodgkin's lymphoma (NHL) is an uncommon lesion involving the spinal epidural space, the usual age for presentation is fourth to fth decade of life. There is male preponderance (66-70%) with male: female ratio of 1.6:1. We present here a case of 48 years old female who presented with complaints of pain at upper back, and difculty in walking due to progressive spastic paraparesis and loss of bladder control. Based on MRI scan which revealed D4-D6 extradural lesion, patient underwent decompressive laminectomy and tumor excision. Histological examination revealed non-Hodgkin's Tcell rich B cell lymphoma following which a detailed workup for search of primary lesion was done which ultimately turned out to be negative. Patient was given adjuvant chemotherapy(R-CHOP). At follow up MRI spine showed no residual tumor at st the end of 1 year. It is concluded that spinal cord compression without any obvious primary lesion elsewhere, requires surgical decompression and tumor removal with adjuvant chemotherapy(R-CHOP) to recover neurological function and to help patient to lead a normal healthy life

<p>Non-Hodgkin's lymphoma (NHL) is an uncommon lesion involving the spinal epidural space, the usual age for presentation is fourth to fth decade of life. There is male preponderance (66-70%) with male: female ratio of 1.6:1. We present here a case of 48 years old female who presented with complaints of pain at upper back, and difculty in walking due to progressive spastic paraparesis and loss of bladder control. Based on MRI scan which revealed D4-D6 extradural lesion, patient underwent decompressive laminectomy and tumor excision. Histological examination revealed non-Hodgkin's Tcell rich B cell lymphoma following which a detailed workup for search of primary lesion was done which ultimately turned out to be negative. Patient was given adjuvant chemotherapy(R-CHOP). At follow up MRI spine showed no residual tumor at st the end of 1 year. It is concluded that spinal cord compression without any obvious primary lesion elsewhere, requires surgical decompression and tumor removal with adjuvant chemotherapy(R-CHOP) to recover neurological function and to help patient to lead a normal healthy life</p>
Keywords
Extradural non-Hodgkin's lymphoma, cord compression, Radiotherapy, R-CHOP, Thoracic spine. T-cell rich B-cell lymphoma (TRBCL)
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