RGUHS Nat. J. Pub. Heal. Sci Vol: 14 Issue: 4 eISSN: pISSN
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Lancelot Lobo1 , Kishan Prasad HL2 , Sujaya Prabhakar3
1 Department of General Surgery, 2Department of Pathology,3 Department of Obstetrics & Gynaecology, K S Hegde Medical Academy of Nitte University, Mangalore, Karnataka, India.
Abstract
Primary choriocarcinoma of ovary is rare. It could be gestational or non-gestational in origin. The distinction between the two is difficult, but necessary, as the non-gestational type has a bad prognosis. We report a case of a pure ovarian choriocarcinoma, likely to be of gestational origin, treated by cytoreductive surgery in combination with post-operative chemotherapy. The patient received 4 cycles of Etoposide/ Metotrexate / Actinomycin D/ Cisplatin/ Etoposide (EMA-CE) regimen with a satisfactory decrease in the serum β-hCG level. There was no evidence of recurrence or metastasis after 6- months follow-up. Our case provides evidence that cytoreductive surgery in combination with post-operative chemotherapy is an effective therapeutic strategy for pure ovarian choriocarcinoma. The pure ovarian choriocarcinoma is aggressive with a high risk of metastasis, close follow-up with serum β-hCG and imaging examinations is essential.
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