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RGUHS Nat. J. Pub. Heal. Sci Vol: 14  Issue: 2 eISSN:  pISSN

Case Report

A Rare Case of Primary Non-Hodgkin's Lymphoma of the Liver in HIV Seropositive Patient

Swamy HM1 , Hosakatti SC 2, Rao Meghana3 , Hubballi Prashant3

 1Professor and Head of the Department, 2Assistant Professor, 3Postgraduates 

Department of Medicine, Karnataka Institute of Medical Sciences, Hubli-580022 

Year: 2013, Volume: 3, Issue: 1, Page no. 51-53,
Views: 656, Downloads: 2
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0.
Abstract

Non Hodgkin's Lymphoma (NHL) is the second most frequent malignancy associated with HIV/AIDS. The majority of NHL associated with HIV/AIDS is known to involve extra-nodal sites such as gastrointestinal tract and central nervous system. Primary NHL of liver is an uncommon neoplasm among these patients. It represents less than 1% of all extra-nodal lymphomas. Ultrasonography and computed tomography scans may be helpful in the diagnosis. Image-guided fine-needle biopsy with histopathology of the liver lesions is the gold standard for the diagnosis of hepatic lymphoma. We report a case of primary hepatic lymphoma as the initial manifestation of AIDS in a patient without any previous infection by hepatitis C or B virus, presenting as multiple and large hepatic masses. 

<p>Non Hodgkin's Lymphoma (NHL) is the second most frequent malignancy associated with HIV/AIDS. The majority of NHL associated with HIV/AIDS is known to involve extra-nodal sites such as gastrointestinal tract and central nervous system. Primary NHL of liver is an uncommon neoplasm among these patients. It represents less than 1% of all extra-nodal lymphomas. Ultrasonography and computed tomography scans may be helpful in the diagnosis. Image-guided fine-needle biopsy with histopathology of the liver lesions is the gold standard for the diagnosis of hepatic lymphoma. We report a case of primary hepatic lymphoma as the initial manifestation of AIDS in a patient without any previous infection by hepatitis C or B virus, presenting as multiple and large hepatic masses.&nbsp;</p>
Keywords
AIDS, Non-Hodgkin lymphoma
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