Hemodialysis Induced Hypoglycemia in Chronic Kidney Disease Patients

<p>A prospective and comparative study was conducted on hundred subjects selected from the patients coming to the dialysis unit, eligible &amp; willing for the study, divided in to two groups of diabetic &amp; non-diabetic (fifty each). Quantitative data like BSL and DSL values were calculated and analyzed along with the Qualitative data like symptoms on hypoglycemia and compared interchangeably with both groups at specific intervals of time.</p> <p>46/100 subjects showed hypoglycemia (27 diabetics, 19 non-diabetics), out of which, 12/46 (11 diabetics, 1 non-diabetic) had symptomatic hypoglycemia, whereas, 34/46 (16 diabetics, 18 non-diabetics) had asymptomatic or occult. Subsequently, the dialysate sugars also showed a statistically significant rise, in both the groups, as the blood sugar levels went down. All this concluding, quantitatively, that the fall in BSL values in diabetics &amp; non-diabetics, was statistically significant in the first half of dialysis i.e. 90mins from the start of dialysis (z = 3.58, p&lt; 0.05 for 30mins &amp; z = 4.9, p&lt;0.05 for 90mins in diabetics &amp; z = 5.6, p&lt; 0.05 for 30mins &amp; z = 6.14, p&lt;0.05 for 90mins in non-diabetics), whereas even if the fall was n't significant statistically in the latter half of dialysis i.e. after 90mins &amp; in post dialysis samples (z = 0.96, p&gt;0.05 in diabetics &amp; z = 1.03, p&gt;0.05 in non-diabetics), it indicated a rise in the BSL, suggestive of recovery from hypoglycemia in diabetic subjects.</p> <p>Quantitatively, the difference in distribution of diabetes &amp; non-diabetes according to the presence or absence of symptoms was statistically 2 significant (x = 5.55, p&lt;0.05), probably suggesting that patients undergoing dialysis should be given mid-dialysis snack to avoid hypoglycemia and it's complications, insulin doses should be adjusted as per dialysis scheduled days &amp; possibility of glucose containing dialysate solution should be explored.</p>