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RGUHS Nat. J. Pub. Heal. Sci Vol No: 10 Issue No: 2  pISSN: 2249-2149

Review Article

A Comparative Pharmacological Study on the Effect of Tagara [Valerina wallichii] and Jatamansi [Nardostachys jatamansi] In the Management of Anidra W.S.R. to Primary Insomnia

Toolika E1, Ravi Mundugaru*,2, Sudhakara .3, Ravishankar B4, Narayana Prakash B5, Suhas Kumar Shetty6, Savitha HP7,

1Toolika E, Department of Manasa Roga, SDM College of Ayurveda, Hassan

2Ravi Mundugaru, Research Officer Pharmacology& Toxicology, SDM Centre for Research in Ayurveda and Allied Sciences, Udupi-574118 Email- ravisdm13@gmail.com

3Sudhakara, Department of Pharmacology& Toxicology, SDM Centre for Research in Ayurveda and Allied Sciences, Udupi.

4Ravishankar B, Department of Pharmacology& Toxicology, SDM Centre for Research in Ayurveda and Allied Sciences, Udupi.

5Narayana Prakash B, Department of Manasa Roga, SDM College of Ayurveda, Hassan

6Suhas Kumar Shetty, Department of Manasa Roga, SDM College of Ayurveda, Hassan

7Savitha HP, Department of Manasa Roga, SDM College of Ayurveda, Hassan

*Corresponding Author:

Ravi Mundugaru, Research Officer Pharmacology& Toxicology, SDM Centre for Research in Ayurveda and Allied Sciences, Udupi-574118 Email- ravisdm13@gmail.com, Email: ravisdm13@gmail.com
Received Date: 2012-12-01,
Accepted Date: 2012-12-20,
Published Date: 2013-01-31
Year: 2013, Volume: 3, Issue: 1, Page no. 8-14,
Views: 277, Downloads: 5
Licensing Information:
CC BY NC 4.0 ICON
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0.
Abstract

The present study was undertaken to evaluate Tagara and Jatamansi for Certain CNS ativities to ascertain the basis for their use as sedative and hypnotics. The drugs were evaluated for hypnotic and sedative, anti anxiety, anti depressant and anti psychotic activities using standard experimental protocol. The data generated suggests that the test drugs Tagara and Jatamansi have complex CNS activity profile which is not easy to actegorize undr general CNS activity profile. Both possess significant anti-anxiety without significant sedative-hypnotic activity. This increases their utility for the patients suffering from anxiety due to sleep disturbances. 

<p>The present study was undertaken to evaluate Tagara and Jatamansi for Certain CNS ativities to ascertain the basis for their use as sedative and hypnotics. The drugs were evaluated for hypnotic and sedative, anti anxiety, anti depressant and anti psychotic activities using standard experimental protocol. The data generated suggests that the test drugs Tagara and Jatamansi have complex CNS activity profile which is not easy to actegorize undr general CNS activity profile. Both possess significant anti-anxiety without significant sedative-hypnotic activity. This increases their utility for the patients suffering from anxiety due to sleep disturbances.&nbsp;</p>
Keywords
Tagara, Jatamansi, Hypnotic and Sedative activity, Anti anxiety, Anti depresant activity
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